What is the Best Flea & Tick Prevention?

For my moggies (who've all passed on) I've always used the flea & tick collars with great success. For my purebred MC Whiskey I intend to use a harness while he is outside in the yard as he can't be trusted to not wander off.

Spot-on treatments seems to be the most used, but perhaps not the most effective at prevention. Flea & Tick collars seem to work, but no one seems to use them anymore. Would a flea/tick the collar interfere with the comfort of a harness?.

My vets seem to like the spot-on, which they sell. I am so confused on what to use or stay away from.

I use the frontline drops you put behind the neck on Hank every few months, he's in the garden everyday chasing frogs till he gets tired and touch wood havent had any sign of the little buggers yet..

Flea and tick collars and any flea preparation sold in pet stores generally do not work and are a waste of money.
Frontline spot-on is the only thing that really works (although other brands are available).
It is cheaper to buy Frontline etc from an online store than from your vet. You don't need a prescription for it (in the UK).

I think you can only buy the normal frontline on line without a prescription the combo still requires one.....
I had a bad breakdown though with the Frontline combo so now use Stronghold which for some reason the cats seem to be a lot happier with having it applied,with frontline one pipette down five cats hiding now five just sit & wait the new sixth we haven't got trained yet....!

our dermatologists recommend stronghold , at the moment i use frontline combo but will swop when finished . the important thing is to follow the instrustions and do it as recommended , dont skimp on the timings x

Thanks for suggestions. I already buy my pet prescriptions, over-the-counter meds, toys, & pet food online as the prices seem to be cheaper. I will look at online pricing for flea & tick control too.